Organo-Metalloid Compounds
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Filtered Search Results
Medchemexpress LLC Azido-PEG5-alcohol | 86770-68-5 | MFCD20134131 | >97.0% | 263.29 g/mol | C10H21N3O5 | 250 MG
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Azido-PEG5-alcohol is a 5-unit polyethylene glycol (PEG) linker bearing an azide and a terminal hydroxyl group, used as a click-chemistry reagent and as a non-cleavable PEG spacer in conjugation and PROTAC synthesis. Purity is ≥97.0%, molecular weight is 263.29 g/mol, and CAS number is 86770-68-5.
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions.
- Compatible with strain-promoted azide-alkyne cycloaddition (SPAAC) with DBCO or BCN.
- Non-cleavable 5-unit PEG spacer to improve solubility and flexibility.
- Available in multiple sizes, including 250 mg.
- High purity suitable for synthetic and conjugation applications.
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Medchemexpress LLC Azido-PEG3-SS-PEG3-azide | 1310827-27-0 | 99.3% | C16H32N6O6S2 | 10MG
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Azido-PEG3-SS-PEG3-azide is a symmetric, cleavable polyethylene glycol (PEG)-based bifunctional linker bearing terminal azide groups and a central disulfide bond. It is designed for bioconjugation and PROTAC synthesis, enabling both copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC), while allowing reductive cleavage for controlled release.
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Medchemexpress LLC Mal-PEG3-NH2 TFA | 2830214-77-0 | 99.1% | 386.32 g/mol | C14H21F3N2O7 | 50 MG
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Mal-PEG3-NH2 TFA is a linear, heterobifunctional polyethylene glycol (PEG) crosslinker supplied as the trifluoroacetic acid (TFA) salt. It contains a maleimide at one end and a primary amine at the other, enabling thiol-to-amine conjugation and use as a non-cleavable linker in PROTAC and bioconjugation workflows. For research use only.
- Provides maleimide and primary amine reactive groups for orthogonal conjugation.
- PEG3 spacer improves aqueous solubility and reduces steric hindrance.
- TFA salt form enhances stability and handling compared with the free base.
- Non-cleavable linker suitable for stable conjugates and PROTAC constructs.
- High purity (>99%) for consistent conjugation performance.
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Medchemexpress LLC NH2-PEG3-C6-Cl | 1261350-60-0 | 267.79 | 50 MG
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NH2-PEG3-C6-Cl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Contains two different ligands connected by a linker
- One is a ligand for an E3 ubiquitin ligase
- The other is for the target protein
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Medchemexpress LLC N-(Boc-PEG3)-N-bis(PEG2-alcohol) | 2055042-60-7 | C25H52N2O11 | 250 MG
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N-(Boc-PEG3)-N-bis(PEG2-alcohol) is a PEG-based PROTAC linker used in the synthesis of Proteolysis Targeting Chimeras (PROTACs). PROTACs are designed to leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins. This product is intended for research use only.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Enables targeted protein degradation via the ubiquitin-proteasome system
- Facilitates connection between an E3 ubiquitin ligase ligand and a target protein ligand
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Medchemexpress LLC Azido-PEG3-DYKDDDDK (TFA) | 1242.20 | 50 MG
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Azido-PEG3-DYKDDDDK (azide-PEG3-FLAG) TFA is a multifunctional fusion tag for the purification of recombinant proteins. It is a click chemistry reagent that contains an azide group. It can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing alkyne groups, or strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Multifunctional fusion tag for the purification of recombinant proteins
- Click chemistry reagent
- Contains an azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) reaction with molecules containing alkyne groups
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups
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Medchemexpress LLC Azido-PEG5-CH2CO2-NHS | 2144777-77-3 | 97% | C16H26N4O9 | 250 MG
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Azido-PEG5-CH2CO2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is a click chemistry reagent containing an Azide group, which allows it to undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker for synthesis
- Click chemistry reagent with azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups
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eMolecules 1076199-21-7 | BocNH-PEG3-CH2CH2Br | Acrotein ChemBio Inc. | MFCD09840081 | 356.257 | C13H26BrNO5 | 97.000 | CC(C)(C)OC(=O)NCCOCCOCCOCCBr | 5g | 705837391
BocNH-PEG3-CH2CH2Br | Acrotein ChemBio Inc. | 1076199-21-7 | MFCD09840081 | 356.257 | C13H26BrNO5 | 97.000 | CC(C)(C)OC(=O)NCCOCCOCCOCCBr | 5g | 705837391
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eMolecules 77544-68-4 | Tos-PEG3 | Medchem Express | MFCD18433414 | 304.360 | C13H20O6S | 98.000 | Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCO | 250mg | 746319413
Tos-PEG3 | Medchem Express | 77544-68-4 | MFCD18433414 | 304.360 | C13H20O6S | 98.000 | Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCO | 250mg | 746319413
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Aobchem 2-(3 -Bromophenoxy)tetrahydro-2H-pyran | ≥95% | CAS 57999-49-2 | C11H13BrO2 | 25g
2-(3 -Bromophenoxy)tetrahydro-2H-pyran | ≥95% | CAS 57999-49-2 | C11H13BrO2 | 25g
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Aobchem 1-Bromo-3-(tert-butoxymethyl)benzene | ≥97% | CAS 414858-17-6 | C11H15BrO | 5g
1-Bromo-3-(tert-butoxymethyl)benzene | ≥97% | CAS 414858-17-6 | C11H15BrO | 5g
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Medchemexpress LLC Dbco-peg3-acid | 2754384-59-1 | 98.4% | 508.56 g/mol | C28H32N2O7 | 10 MG
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DBCO-PEG3-acid is a dibenzocyclooctyne (DBCO)-containing PEG linker designed for copper-free click chemistry (strain-promoted alkyne-azide cycloaddition) in bioconjugation and antibody-drug conjugate synthesis. It is a non-cleavable linker supplied as a solid for laboratory use.
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Medchemexpress LLC Ms-PEG5-t-butyl ester | 870487-48-2 | C₁₆H₃₂O₉S | 250 MG
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Ms-PEG5-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
- PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
- PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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Medchemexpress LLC N-(Amino-PEG3)-N-bis(PEG4-Boc) | 2353409-57-9 | 98.0% | C38H76N2O15 | 100 MG
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N-(Amino-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs consist of two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets the protein of interest. These molecules exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Utilized in PROTAC synthesis
- Applicable in cancer-programmed cell death research
- Connects two different ligands for PROTAC formation
- Targets E3 ubiquitin ligase and protein of interest
- Exploits intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC 2-(2-(2-bromoethoxy)ethoxy)ethyl methanesulfonate | 2702323-73-5 | 95.0% | 291.16 | C7H15BrO5S | 5 MG
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Br-PEG3-MS is a brominated, PEG-based PROTAC linker (methanesulfonate) designed for use in chemical synthesis of PROTACs and other bifunctional molecules. It provides a short PEG3 spacer with a reactive leaving group for conjugation chemistry, enabling efficient formation of linkages between ligands under standard organic conditions. For research use only.
- PEG3 spacer with a terminal bromide and methanesulfonate leaving group.
- Suitable for linker synthesis and nucleophilic substitution reactions.
- High purity (95.0% by NMR) for reliable synthetic performance.
- Low molecular weight facilitates handling in small-scale reactions.
- Available in multiple small pack sizes to support medicinal chemistry workflows.
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