Organo-Metalloid Compounds

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856 – 870 of 2,133 results

856

Apexbio Technology LLC OSI-930 728033-96-3 5mg

OSI-930 (CAS 728033-96-3) is a small molecule inhibitor targeting multiple receptor tyrosine kinases including Flt1 (IC 8 nM) KDR/VEGFR2 (IC 9 nM) CSF-1R (IC 15 nM) Lck c-Raf and Kit (IC 80 nM) In cellular studies OSI-930 inhibits proliferation and induces apoptosis in HMC-1 cells whose survival is dependent on Kit signaling while exhibiting minimal effects on COLO-205 cells under standard conditions Additionally OSI-930 inactivates cytochrome P450 3A4 in a time- and concentration-dependent manner and alters its spectral properties These characteristics make OSI-930 a valuable tool compound for investigating receptor tyrosine kinase signaling pathways and related cellular processes in cancer research

Pricing & Availability

857

eMolecules 80522-42-5 | Ambeed | Triisopropylsilyl trifluoromethanesulfonate | 25g | 525166541 | A274403 | MFCD00009913 | 306.42 | C10H21F3O3SSi

Ambeed | Triisopropylsilyl trifluoromethanesulfonate | 25g | 525166541 | A274403 | 80522-42-5 | MFCD00009913 | 306.420 | C10H21F3O3SSi

Pricing & Availability

858

Medchemexpress LLC Chlorotriethylsilane | 994-30-9 | 98.3% | 150.72 g/mol | C6H15ClSi | 100 G

Chlorotriethylsilane (triethylsilyl chloride) is an organosilicon reagent used in organic synthesis to introduce the triethylsilyl (TES) protecting group and to perform silylation reactions. It is supplied as a colorless to light yellow liquid with typical purity of 98.3% and is available in multiple packaging sizes.

Used for silylation and introducing triethylsilyl (TES) protecting groups.
Colorless to light yellow liquid.
Typical purity 98.3%.
Molecular formula C6H15ClSi, molecular weight 150.72 g/mol.
Available in 25 g, 50 g, 100 g, and 500 g packaging.
Certificate of analysis available.

Pricing & Availability

859

Medchemexpress LLC EGGGG-PEG8-amide-bis(deoxyglucitol) | 2842855-38-1 | MFCD27995527 | >98.9% | C49H91N9O28 | 25 MG

EGGGG-PEG8-amide-bis(deoxyglucitol) is a cleavable ADC linker. It is used in Antibody-drug Conjugate/ADC Related research.

Product type: ADC linker
Classification: Cleavable
Appearance: Solid-liquid mixture
Color: White to off-white
Intended use: For research use only; not for sale to patients

Pricing & Availability

860

Medchemexpress LLC NH-bis(C2-PEG1-azide) | 2100306-81-6 | C8H17N7O2 | 50 MG

NH-bis(C2-PEG1-azide) is a PEG-based PROTAC linker used in the synthesis of PROTACs. It acts as a click chemistry reagent, featuring an azide group that enables participation in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne groups, and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.

PEG-based PROTAC linker
Utilized in PROTAC synthesis
Functions as a click chemistry reagent
Contains an azide group
Capable of copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
Can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions

Pricing & Availability

861

Medchemexpress LLC N-(Azido-PEG4)-N-bis(PEG4-acid) | 2093152-80-6 | 100 MG

N-(Azido-PEG4)-N-bis(PEG4-acid) is a PROTAC linker belonging to the PEG class, used for synthesizing PROTAC molecules. It is a click chemistry reagent containing an Azide group, which can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. It can also participate in strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

PROTAC linker belonging to the PEG class
Used for synthesizing PROTAC molecules
Click chemistry reagent containing an Azide group
Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules
Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups
Utilizes the intracellular ubiquitin-proteasome system to selectively degrade target proteins

Pricing & Availability

862

Apexbio Technology LLC Epidermal Growth Factor Receptor Peptide (985-996) 96249-43-3 10mg

Epidermal Growth Factor Receptor Peptide (985-996) (CAS 96249-43-3) corresponds to a C-terminal segment of the EGFR protein involved in receptor autophosphorylation EGFR a transmembrane receptor tyrosine kinase undergoes activation upon ligand binding triggering receptor dimerization and subsequent phosphorylation of specific tyrosine residues within its C-terminus including the 985-996 region This phosphorylation facilitates recruitment of SH2 domain-containing signaling proteins thereby initiating pathways such as MAPK Akt and JNK which regulate cell proliferation migration and adhesion This peptide serves as a useful research tool for elucidating EGFR-mediated signaling and studying kinase-substrate interactions in cellular models

Pricing & Availability

863

eMolecules 1-((2-(TRIMETHYLSILYL)ETHOXY)METHYL)-1H-1,2,4-TRIAZOLE | 136118-56-4 | MFCD27997533 | 1g

AstaTech | 1-((2-(TRIMETHYLSILYL)ETHOXY)METHYL)-1H-1,2,4-TRIAZOLE | 1g | 499932580 | 73093 | 95.000 | 136118-56-4 | MFCD27997533 | 199.329 | C8H17N3OSi

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864

Alkali Scientific Acrylamide/bis Acrylamide, 37.5:1 Ratio Solution, 500 Milliliters

Acrylamide/bis Acrylamide, 37.5:1 Ratio Solution, 500 Milliliters, is a liquid solution for preparing polyacrylamide gels that separate larger proteins and other large biomolecules. The 37.5:1 acrylamide-to-bis-acrylamide ratio creates a gel matrix that is ideal for resolving larger molecules in electrophoresis. This ready-to-use solution streamlines the gel preparation process by eliminating the need for mixing dry reagents. It is commonly used in protein research, biomolecule characterization, and molecular biology applications where the separation of larger proteins or nucleic acids is required for detailed analysis.

Pricing & Availability

865

Medchemexpress LLC Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate | 632-93-9 | MFCD00005950 | 99.5% | 267.32 g/mol | C14H21NO4 | 10 G

Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate is a diethyl ester of a 1,4-dihydropyridine used as a small-molecule reagent or synthetic intermediate in research laboratories.

White to off-white solid suitable for laboratory use.
Molecular formula C14H21NO4; molecular weight 267.32 g/mol.
High purity (99.5% assay) appropriate for analytical and synthetic work.
Stable as powder at -20°C (up to 3 years) or 4°C (up to 2 years).
In solvent recommended storage -80°C (6 months) or -20°C (1 month).
Available in multiple sizes, including 10 G, for flexibility in experiments.
Used as a dihydropyridine ester intermediate or reagent in chemical research.

Pricing & Availability

866

eMolecules Oakwood Chemical Sodium bis (trimethylsilyl) amide 1M in THF 3kg 629469699 S14981 0 000 1070-89-9 MFCD00009835 183 377 C6H18NNaSi2

Oakwood Chemical Sodium bis (trimethylsilyl) amide 1M in THF 3kg 629469699 S14981 0 000 1070-89-9 MFCD00009835 183 377 C6H18NNaSi2

Pricing & Availability

867

eMolecules 1394119-83-5 | {3-[(tert-butyldimethylsilyl)oxy]cyclobutyl}methanol | MFCD23106334 | 1g

AstaTech | 23-DIFLUORO-4-NITROBENZOIC ACID | 1g | 233612392 | 22824 | 98.000 | 1806370-35-3 | MFCD27922146 | 203.101 | C7H3F2NO4

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Pricing & Availability

868

Medchemexpress LLC GSK2807 trifluoroacetate | 2245255-66-5 | 99.8% | 566.53 | C21H33F3N8O7 | 100 MG

GSK2807 trifluoroacetate is a SAM-competitive small-molecule inhibitor of the histone methyltransferase SMYD3, reported with Ki = 14 nM and IC50 = 130 nM. It is provided as the trifluoroacetate salt for research use in biochemical and cell-based studies of methylation-dependent signaling.

High potency against SMYD3 (Ki = 14 nM; IC50 = 130 nM).
SAM-competitive mechanism of action.
Supplied as trifluoroacetate (TFA) salt.
High chemical purity (>99.8%).
Molecular weight 566.53 g/mol.
Suitable for biochemical and cell-based assay development.

Pricing & Availability

869

eMolecules 1229454-44-7 | 5-(TERT-BUTYLDIMETHYLSILYLOXY)-4,4-DIMETHYL-3-OXOPENTANENITRILE | MFCD26399496 | 1g

Medchem Express | RP 70676 | 5mg | 415685844 | HY-101576 | 136609-26-2 | MFCD00907619 | 416.590 | C25H28N4S

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870

eMolecules 3-(t-Butyldimethylsilyloxy)-4-chloro-2-fluorophenylboronic acid | 1256354-94-5 | MFCD17015761 | 1g

Combi-Blocks | 3-(t-Butyldimethylsilyloxy)-4-chloro-2-fluorophenylboronic acid | 1g | 117524740 | BB-6525 | 95.000 | 1256354-94-5 | MFCD17015761 | 304.620 | C12H19BClFO3Si

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Organo-Metalloid Compounds

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Apexbio Technology LLC OSI-930 728033-96-3 5mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Chlorotriethylsilane | 994-30-9 | 98.3% | 150.72 g/mol | C6H15ClSi | 100 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC EGGGG-PEG8-amide-bis(deoxyglucitol) | 2842855-38-1 | MFCD27995527 | >98.9% | C49H91N9O28 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC NH-bis(C2-PEG1-azide) | 2100306-81-6 | C8H17N7O2 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC N-(Azido-PEG4)-N-bis(PEG4-acid) | 2093152-80-6 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC Epidermal Growth Factor Receptor Peptide (985-996) 96249-43-3 10mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Alkali Scientific Acrylamide/bis Acrylamide, 37.5:1 Ratio Solution, 500 Milliliters Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate | 632-93-9 | MFCD00005950 | 99.5% | 267.32 g/mol | C14H21NO4 | 10 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC GSK2807 trifluoroacetate | 2245255-66-5 | 99.8% | 566.53 | C21H33F3N8O7 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More